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Publications

Read on to explore CCEDRRN's published papers and manuscripts

Development of the Canadian COVID-19 Emergency Department Rapid Response Network population-based registry: a methodology study

March 17, 2021

Corinne M. Hohl, Rhonda J. Rosychuk, Andrew D. McRae, Steven C. Brooks, Patrick Archambault, Patrick T. Fok, Philip Davis, Tomislav Jelic, Joel P. Turner, Brian H. Rowe, Éric Mercier, Ivy Cheng, John Taylor, Raoul Daoust, Robert Ohle, Gary Andolfatto, Clare Atzema, Jake Hayward, Jaspreet K. Khangura, Megan Landes, Eddy Lang, Ian Martin, Rohit Mohindra, Daniel K. Ting, Samuel Vaillancourt, Michelle Welsford, Baljeet Brar, Tara Dahn, Hana Wiemer, Krishan Yadav, Justin W. Yan, Maja Stachura, Colleen McGavin, Jeffrey J. Perry and Laurie J. Morrison; for the Canadian COVID-19 Emergency Department Rapid Response Network investigators and for the Network of Canadian Emergency Researchers and the Canadian Critical Care Trials Group
CMAJ Open 2021, 9 (1): E261-E270; DOI: https://doi.org/10.9778/cmajo.20200290

CCEDRRN COVID-19 Infection Score (CCIS): development and validation in a Canadian cohort of a clinical risk score to predict SARS-CoV-2 infection in patients presenting to the emergency department with suspected COVID-19

December 2, 2021

Andrew D McRae, Corinne M Hohl, Rhonda J Rosychuk, Shabnam Vatanpour, Gelareh Ghaderi, Patrick M Archambault, Steven C Brooks, Ivy Cheng, Philip Davis, Jake Hayward, Eddy S Lang, Robert Ohle, Brian H. Rowe, Michelle Welsford, Krishan Yadav, Laurie J Morrison, Jeffrey J. Perry, Canadian COVID-19 Emergency Department Rapid Response Network (CCEDRRN) investigators for the Network of Canadian Emergency Researchers and the Canadian Critical Care Trials Group

BMJ Open 2021 Dec 2;11(12):e055832; DOI: 10.1136/bmjopen-2021-055832 

Derivation and Validation of a Clinical Score to Predict Death among Non-Palliative COVID-19 Patients Presenting to Emergency Departments: The CCEDRRN COVID Mortality Score

February 8, 2022

Corinne M. Hohl, Rhonda J. Rosychuk, Patrick M. Archambault, Fiona O’Sullivan, Murdoch Leeies, Éric Mercier, Gregory Clark, Grant D. Innes, Steven C. Brooks, Jake Hayward, Vi Ho, Tomislav Jelic, Michelle Welsford, Marco L.A. Sivilotti, Laurie J. Morrison, Jeffrey J. Perry

CMAJ Open February 08, 2022 10 (1) E90-E99; DOI: https://doi.org/10.9778/cmajo.20210243

Treatments, Resource Utilization, and Outcomes of COVID-19 Patients Presenting to Emergency Departments Across Pandemic Waves: An Observational Study by the Canadian COVID-19 Emergency Department Rapid Response Network (CCEDRRN)

April 1, 2022

Hohl, C.M., Rosychuk, R.J., Hau, J.P. et al. Treatments, resource utilization, and outcomes of COVID-19 patients presenting to emergency departments across pandemic waves: an observational study by the Canadian COVID-19 Emergency Department Rapid Response Network (CCEDRRN). Can J Emerg Med 24, 397–407 (2022). https://doi.org/10.1007/s43678-022-00275-3

Diagnostic Yield of Screening for SARS-CoV-2 among Patients Admitted for Alternate Diagnoses

August 10, 2022

Phil Davis, Rhonda J. Rosychuk, Jeffrey P Hau, Ivy Cheng, Andrew D. McRae, Raoul Daoust, Eddy Lang, Joel Turner, Jaspreet Khangura, Patrick T. Fok, Maja Stachura, Baljeet Brar, Corinne Hohl on behalf of CCEDRRN investigators, and for the Network of Canadian Emergency Researchers and the Canadian Critical Care Trials Group, et al Diagnostic yield of screening for SARS-CoV-2 among patients admitted to hospital for alternate diagnoses: an observational cohort study BMJ Open 2022;12:e057852. DOI: https://bmjopen.bmj.com/content/12/8/e057852 

Reducing barriers to accessing administrative data on SARS-CoV-2 vaccination for research

July 18, 2022

Andrew D. McRae, Patrick Archambault, Patrick Fok, Hana Wiemer, Laurie J. Morrison and Matthew Herder; for the Canadian COVID-19 Emergency Department Rapid Response Network Investigators, Reducing barriers to accessing administrative data on SARS-CoV-2 vaccination for research CMAJ July 18, 2022 194 (27) E943-E947; DOI: https://doi.org/10.1503/cmaj.211712

Antiviral treatment for COVID-19: ensuring evidence is applicable to current circumstances

July 25, 2022

Corinne M. Hohl and Andrew D. McRae. 

CMAJ July 25, 2022 194 (28) E996-E997; DOI: https://doi.org/10.1503/cmaj.221012

Sensitivity and Diagnostic Yield of the First SARS-CoV-2 Nucleic Acid Amplification Test Performed for Patients Presenting to the Hospital

October 12, 2022

Corinne M. Hohl, Jeffrey P. Hau, Samuel Vaillancourt, Jennifer Grant, Steven C. Brooks, Laurie J. Morrison, Jeffrey J. Perry, Rhonda J. Rosychuk for the CCEDRRN investigators for the Network of Canadian Emergency Researchers and the Canadian Critical Care Trials Group Sensitivity and Diagnostic Yield of the First SARS-CoV-2 Nucleic Acid Amplification Test Performed for Patients Presenting to the Hospital. JAMA Netw Open. 2022;5(10):e2236288. doi:10.1001/jamanetworkopen.2022.36288

Patient-reported health outcomes of SARS-COV-2 tested patients presenting to emergency departments: a propensity-score matched prospective cohort study

December 1, 2022

Rajan Bola, Jason Sutherland, Rachel A. Murphy, Murdoch Leeies, Lars Grant, Jake Hayward, Patrick Archambault, Lorraine Graves, Tamara Rose, Corinne Hohl,  Patient-reported health outcomes of SARS-COV-2 tested patients presenting to emergency departments: a propensity-score matched prospective cohort study,  Public Health, 2022,  https://doi.org/10.1016/j.puhe.2022.11.016

Derivation and validation of a clinical decision rule to risk-stratify COVID-19 patients discharged from the emergency department: The CCEDRRN COVID discharge score

December 22, 2022

Brooks SC, Rosychuk RJ, Perry JJ, Morrison LJ, Wiemer H, Fok P, Rowe BH, Daoust R, Vatanpour S, Turner J, Landes M, Ohle R, Hayward J, Scheuermeyer F, Welsford M, Hohl C; Canadian COVID‐19 Rapid Response Network (CCEDRRN) for the Network of Canadian Emergency Researchers (NCER) and the Canadian Critical Care Trials Group (CCCTG). Derivation and validation of a clinical decision rule to risk-stratify COVID-19 patients discharged from the emergency department: The CCEDRRN COVID discharge score. J Am Coll Emerg Physicians Open. 2022 Dec 22;3(6):e12868. doi: 10.1002/emp2.12868.

Prognostic association between d-dimer thresholds and 30-day pulmonary embolism diagnosis among emergency department patients with suspected SARS-CoV-2 infection: a Canadian COVID-19 Emergency Department Rapid Response Network Study

January 10, 2023

Lin K, Xu K, Daoust R, Taylor J, Rosychuk RJ, Hau JP, Davis P, Clark G, McRae AD, Hohl CM; Canadian COVID-19 Emergency Department Rapid Response Network (CCEDRRN) investigators for the Network of Canadian Emergency Researchers, the Canadian Critical Care Trials Group. Prognostic association between d-dimer thresholds and 30-day pulmonary embolism diagnosis among emergency department patients with suspected SARS-CoV-2 infection: a Canadian COVID-19 Emergency Department Rapid Response Network study. CJEM. 2023 Jan 10. doi: 10.1007/s43678-022-00440-8

Intubation practices and outcomes for patients with suspected or confirmed COVID-19: a national observational study by the Canadian COVID-19 Emergency Department Rapid Response Network (CCEDRRN)

April 5, 2023

Leeies, M., Rosychuk, R.J., Ismath, M. et al. Intubation practices and outcomes for patients with suspected or confirmed COVID-19: a national observational study by the Canadian COVID-19 Emergency Department Rapid Response Network (CCEDRRN). Can J Emerg Med (2023). https://doi.org/10.1007/s43678-023-00487-1

The burden of incidental SARS‑CoV‑2 infections in hospitalized patients across pandemic waves in Canada

April 24, 2023

McAlister, F.A., Hau, J.P., Atzema, C. et al. The burden of incidental SARS-CoV-2 infections in hospitalized patients across pandemic waves in Canada. Sci Rep 13, 6635 (2023). https://doi.org/10.1038/s41598-023-33569-2

Research recruitment and consent methods in a pandemic: a qualitative study of COVID-19 patients’ perspectives

May 11, 2023

Small, S.S., Lau, E., McFarlane, K. et al. Research recruitment and consent methods in a pandemic: a qualitative study of COVID-19 patients’ perspectives. BMC Med Res Methodol 23, 113 (2023). https://doi.org/10.1186/s12874-023-01933-5

Accuracy of Self-Reported COVID-19 Vaccination Status Compared With a Public Health Vaccination Registry in Québec: Observational Diagnostic Study

June  16, 2023

Archambault PM, Rosychuk RJ, Audet M, Bola R, Vatanpour S, Brooks SC, Daoust R, Clark G, Grant L, Vaillancourt S, Welsford M, Morrison LJ, Hohl CM, Canadian COVID-19 Emergency Department Rapid Response Network (CCEDRRN) investigators, Network of Canadian Emergency Researchers, Canadian Critical Care Trials Group. Accuracy of Self-Reported COVID-19 Vaccination Status Compared With a Public Health Vaccination Registry in Québec: Observational Diagnostic Study. JMIR Public Health Surveill 2023;9:e44465.  DOI: 10.2196/44465

Comparing methods to classify admitted patients with SARS-CoV-2 as admitted for COVID-19 versus with incidental SARS-CoV-2: A cohort study

September  26, 2023

Hohl CM, Cragg A, Purssel E, McAlister FA, Ting DK, Scheuermeyer F, et al. (2023) Comparing methods to classify admitted patients with SARS-CoV-2 as admitted for COVID-19 versus with incidental SARS-CoV-2: A cohort study. PLoS ONE 18(9): e0291580. https://doi.org/10.1371/journal.pone.0291580

Characterizing intubation practices in response to the COVID-19 pandemic: a survey of the Canadian COVID-19 Emergency Department Rapid Response Network (CCEDRRN) sites

November  24, 2023

Ismath, M., Black, H., Hrymak, C. et al. Characterizing intubation practices in response to the COVID-19 pandemic: a survey of the Canadian COVID-19 Emergency Department Rapid Response Network (CCEDRRN) sites. BMC Emerg Med 23, 139 (2023). https://doi.org/10.1186/s12873-023-00911-w

Characteristics and outcomes of patients with COVID-19 who return to the emergency department: a multicentre observational study by the Canadian COVID-19 Emergency Department Rapid Response Network (CCEDRRN)

February  16, 2024

Rhonda J Rosychuk, Jaspreet K Khangura, Sylvia S Ortiz, Ivy Cheng, Iwona A Bielska, Justin Yan, Laurie J Morrison, Jake Hayward, Lars Gratn, Corinne M Hohl. Characteristics and outcomes of patients with COVID-19 who return to the emergency department: a multicentre observational study by the Canadian COVID-19 Emergency Department Rapid Response Network (CCEDRRN). Emergency Medicine Journal Published Online First: 16 February 2024. doi: 10.1136/emermed-2023-213277

Administrative data ICD-10 diagnostic codes identifies most lab-confirmed SARS-CoV-2 admissions but misses many discharged from the Emergency Department

March  12, 2024

Moura CS, Morrison LJ, Hohl CM, Grant L, Pilote L, Neville A, Hau JP, Bernatsky S; and the Canadian COVID-19 Emergency Department Rapid Response Network (CCEDRRN) investigators; Network of Canadian Emergency Researchers; Canadian Critical Care Trials Group. Administrative data ICD-10 diagnostic codes identifies most lab-confirmed SARS-CoV-2 admissions but misses many discharged from the Emergency Department. Sci Rep. 2024 Mar 12;14(1):6008. doi: 10.1038/s41598-023-49501-7. PMID: 38472258

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